COVID-19: Zapped by Laser

Methods

Femtosecond laser irradiation

Proposed model for USP laser-induced viral capsid defect

Results

USP laser-treated virus is internalized by host cells

Electron microscopy shows cellular internalization of USP laser-treated MCMV
Fluorescence microscopy shows cellular internalization of USP laser-treated MCMV

Conclusion

  • We reveal evidence supporting a functional capsid defect in viruses inactivated by ultrashort pulsed laser treatment.
  • USP laser targeting of capsids is a unique mechanism with advantages against rapidly mutating or drug-resistant pathogens.
  • USP laser treatment has applications in pathogen reduction, antiviral treatments, and vaccine development.

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An Explorer of the Infinite Multiverse . MS - Physics , Northeastern University.

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Aayushi Vaish

Aayushi Vaish

An Explorer of the Infinite Multiverse . MS - Physics , Northeastern University.

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